Prostaglandins and Glaucoma

Prostaglandins and glaucoma.

Human aqueous humour was found to contain a substance which contracted the rat stomach strip. The mean activity was significantly higher in specimens from open angle glaucoma cases than in specimens from patients with cataract. The pharmacological and chromatographic properties of the active material were studied in aqueous humour obtained from cadavers; activity seemed to be due to prostagland...

Comparison of b-Blockers and Prostaglandins Treatments in Primary Open-Angle Glaucoma

The main protective element of ganglion cells in hypertensive glaucoma is the reduction of intraocular pressure (IOP) [1]. IOP can be reduced in various ways. At present, the most commonly used drugs are β-blockers and prostaglandins. The study of Holmstrom et al [6], who observed the cost-effectiveness of bimatoprost, latanoprost and timolol in treatment of primary open angle glaucoma in five ...

Prostaglandins

Knowledge of the structure and synthesis of antibodies (immunoglobulins) has developed to a remarkable degree in the last decade. Distinct classes of immunoglobulin (yG, yM, -yA, yD, yE, and their subgroups) have been identified and shown to consist of fixed numbers of light and heavy polypeptide chains organized in pairs. Each polypeptide has a segment of variable amino acid sequence; the spec...

[Prostaglandins].

Quality of life of glaucoma patients under medical therapy with different prostaglandins

PURPOSE To assess the quality of life of glaucoma patients under medical therapy with different prostaglandin analogs. METHODS A cross-sectional study of consecutive glaucoma patients was designed. We assessed the patients' quality of life through the Brazilian 25-question version of the National Eye Institute Visual Functioning Questionnaire, comprising 12 subscales (general health, general ...